Since Catalan Dragons joined the Super League in 2006, there have been some highs and lows for Wolves fans.
Here we look at the top 10 moments in the clashes between the two sides…
1. Inaugural trip
Wolves fans first made what would become an annual pilgrimage to Perpignan in 2006.
An estimated 4,000 fans packed the town in the south of France to watch Wolves win 44-16.
Paul Wood, Ben Westwood and Logan Swann were among the try scorers.
2. Semi final success
Wolves took on the French side in 2010 for a place in a second successive Challenge Cup final.
And on a sunny day in Widnes, they were at their irresistible best, romping to a 54-12 win.
The highlight was a majestic piece of skill by David Solomona in the run up to an early try.
3. Olympic joy
For one season only, the trip to Perpignan was replaced by a visit to Barcelona.
Wolves took on the Dragons in the magnificence of the Olympic Stadium in 2009 – and thousands of Warrington fans were there on that June night.
Jon Clarke scored the decisive try in a 24-12 win.
4. Play-off heartbreak
However, it was heartbreak in 2008.
Wolves went to Perpignan in a play-off clash in September.
But they were beaten up mentally and physically and crashed to a 46-8 loss.
5. Happy Monday
A Monday night game under the lights was one for the rugby league purist.
Defences were on top as Wolves beat Catalan 15-6 in July 2012, with Ryan Atkins among the scorers.
6. Quarter final win
Just weeks after an embarrassing Super League loss, Wolves were back in Perpignan for a 2012 Challenge Cup quarter final clash.
And they secured a vital 32-22 win, as they went on to lift the cup at Wembley for the third time in four years in August.
7. Debut season upset
Wolves first took on Catalan in March 2006.
And despite it being their debut season, they upset the ambitious Wolves in a 28-26 win at The Halliwell Jones Stadium.
8. Flying high
Wolves were flying high and aiming for their first Super League leader’s crown in 2011.
And a late Lee Briers interception was key as Wolves swooped to a 25-12 win in mid August at the Stade Gilbert Brutus.
9. Dragons slayed
Despite missing Chris Hicks, Wolves were at their dynamic best in 2010 as they racked up their biggest home win over the Dragons.
Richie Myler and Micky Higham were among the scorers in a 40-6 drubbing.
10. A ‘Lowe’ blow
A dismal start to the season included a 40-20 reversal at The Halliwell Jones Stadium in February 2009.
This defeat to Catalan was one of the results that led to the departure of Jimmy Lowes.